{"id":899,"date":"2021-11-18T08:49:36","date_gmt":"2021-11-18T03:49:36","guid":{"rendered":"https:\/\/cemb.edu.pk\/wp\/?page_id=899"},"modified":"2025-06-02T11:55:07","modified_gmt":"2025-06-02T06:55:07","slug":"achievements","status":"publish","type":"page","link":"https:\/\/www.cemb.edu.pk\/?page_id=899","title":{"rendered":"Achievements"},"content":{"rendered":"\t\t
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MAJOR ACHIEVEMENTS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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RESEARCH AND DEVELOPMENT<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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  • Transgenic cotton plants containing double gene GUSP1 and HSP70 and LTP are developed which are tolerant against heat and drought<\/li>\n
  • Approvals for CKC-5 (triple-gene) from Punjab Seed council and CKK (five-gene) insect-resistant and weedicide-tolerant cotton variety for field trial permission from NBC<\/li>\n
  • Salt-tolerant and drought-resistant cotton varieties have been successfully developed and subjected to field- testing<\/li>\n
  • Developed pest resistant potato through genome editing and subjected to field evaluation<\/li>\n
  • Developed True Potato Seed through breeding longer shelf-life potato and pest resistant<\/li>\n
  • Discovered novel bacteriophages indigenously, that offer significant potential to combat critical health  challenges such as infections caused by Multi Drug Resistant (MDR) Bacteria<\/li>\n
  • miRNA-based Drug-Resistant genes silencing in cancer cell lines, were performed at molecular level<\/li>\n
  • Conducted initial field trials of the larvicidal transgenic algae on the floating treatment wetlands (FTWs)<\/li>\n
  •  Assessed the immunogenicity of the Chlamydomonas reinhardtii expressed influenza CTB-M2e fusion protein in mice<\/li>\n
  • Identified the potential therapeutic agents against Epilepsy and Parkinson\u2019s disease and reported the four medicinal plants with potential anticancer activity<\/li>\n
  • Genetic variations of 30 InDels markers in Azad Jammu and Kashmir Population were identified<\/li>\n
  • Downstream process development\/optimization for the process development of Filgrastim (B<\/li>\n
  • FMDV polyepitope vaccine protein was expressed in E. coli, leading to successful antibody production<\/li>\n
  • The compound Reserpine has been identified as a strong liver anti-fibrotic agent. The compound Reserpine ameliorated liver fibrosis by targeting the Keap1\/Nrf2 pathway<\/li>\n
  • The potential significance of targeting MALAT1 as a therapeutic strategy for breast cancer was identified<\/li>\n
  • The compounds Betanin and Glycine Betaine downregulated expression of dengue-2 NS3 expression.<\/li>\n
  • Coffea arabica extract was shown to have anti-inflammatory and antiarthritic effect in vitro and in vivo<\/li>
  • Demonstrated that Cassia Angustifolia-primed ASCs and Plantago lanceolata and Tussilago farfara-mediated human adipose-derived stem cell therapy effectively enhance burn wound healing<\/li>\n
  • Exosome investigation for tendon injury repair is in process<\/li>
  • Developed stem cell derived exosome therapy for of liver fibrosis in rat models<\/li>\n
  • Developed chitosan-sodium percarbonate-based hydrogels with sustained oxygen release, angiogenic and wound healing properties<\/li>\n
  • Identification of potent senolytic drugs capable of eliminating senescent cells in in vitro diabetic cellular model<\/li>\n
  • Clinical trials investigating the efficacy of ASCs supplemented with platelet rich plasma for diabetic foot ulcer patients in collaboration with JBRSC, Lahore, are ongoing with promising therapeutic outcomes<\/li>
  • Clinical trials for Osteoarthritis and spinal cord injury patients are ongoing<\/li>\n
  • Novel Variants identified in NAV3 gene, a neuronal morphogenesis protein, cause intellectual disability, developmental delay, and microcephaly<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    COMMERCIALIZATION\/ INDUSTRY\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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    • Set up commercial facilities for DNA testing, Qubit quantification and cost-effective BRCA1\/2 screening for cancers<\/li>\n
    • A three-gene cotton variety CEMB-AAS3 was recommended by the Varietal Evaluation Committee, PCCC <\/li>\n
    • Conducted pharmacokinetics and drug toxicity studies of Semaglutide for the biopharmaceutical industry, valued at PKR 1.6 million<\/li>\n
    • Produced PCR Enzymes and kits for in-house use, worth PKR 4.6 million<\/li>\n
    • Revived Molecular diagnostics laboratory for hepatitis testing<\/li>\n\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      GRANTS \/ FUNDINGS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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      • Four TDF projects: PKR 46 million; twenty-six PU Projects: PKR 5.8 million; a CPEC project: PKR 12.963 million; 1 WHO project (AP24-01787): PKR 2.5 million<\/li>\n
      • Ongoing: European Foundation: \u20ac125,000; Islamic Development Bank: 38.36 million PKR; Turkiye industrial: USD 25,000<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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        PATENTS\/MOUs\/AGREEMENTS AND COLLABORATIONS<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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        • 01 Patent awarded <\/li>
        • 04 submitted<\/li>
        •  Signed 10 MOUs<\/li>
        •  Agreements and several collaborations with different institutions at National & International levels<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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          ACADEMIA<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t
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          • Produced 48 M.Phil and 12 Ph.Ds. Published 89 Research Articles (impact factor of 261.614), 10 Book Chapters.<\/li>
          • \nCEMB organized 28 conferences\/scientific events, faculty and students actively participated in national and international conferences, symposia, seminars and training workshops.<\/li>
          • \nCEMB provided internships to 53 students from institutions all over Pakistan. <\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t
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            \n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"

            MAJOR ACHIEVEMENTS RESEARCH AND DEVELOPMENT Transgenic cotton plants containing double gene GUSP1 and HSP70 and LTP are developed which are tolerant against heat and drought Approvals for CKC-5 (triple-gene) from Punjab Seed council and CKK (five-gene) insect-resistant and weedicide-tolerant cotton variety for field trial permission from NBC Salt-tolerant and drought-resistant cotton varieties have been successfully […]<\/p>\n","protected":false},"author":96739698,"featured_media":911,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-899","page","type-page","status-publish","has-post-thumbnail","hentry","entry","has-media"],"_links":{"self":[{"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=\/wp\/v2\/pages\/899","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=\/wp\/v2\/users\/96739698"}],"replies":[{"embeddable":true,"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=899"}],"version-history":[{"count":76,"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=\/wp\/v2\/pages\/899\/revisions"}],"predecessor-version":[{"id":17493,"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=\/wp\/v2\/pages\/899\/revisions\/17493"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=\/wp\/v2\/media\/911"}],"wp:attachment":[{"href":"https:\/\/www.cemb.edu.pk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}