Dr. Maria tayyab baig

Assistant Professor

Stem Cells Lab
e-mail: maria.tayyab@cemb.edu.pk

Dr. Maria Tayyab Baig embarked on her professional journey by joining the Centre of Excellence in Molecular Biology (CEMB) in 2008, shortly after obtaining her BSc Hons. in Microbiology and Molecular Genetics from the University of Punjab in 2007. Since then, she has held the role of a research officer in the Stem Cell and Regenerative Medicine Lab. Her pioneering work includes the establishment of laboratory protocols for isolating stem cells from adipose tissue. A significant portion of her research has been dedicated to addressing liver fibrosis through innovative stem cell therapies.
In 2013, Dr. Maria enrolled in the MPhil Molecular Biology program at CEMB, successfully graduating in 2015 with an outstanding 4.0 CGPA, thereby securing well-deserved gold medals.
Subsequently, in October 2015, she embarked on her Ph.D. journey in the Molecular Biology program at CEMB, culminating in her successful completion of the Ph.D. program in 2022. 
Presently, Dr. Maria’s research thrust revolves around harnessing the potential of stem cells to combat liver diseases such as fibrosis, cirrhosis, and hepatocellular carcinoma. She utilizes advanced molecular techniques like Real Time PCR, Western blotting, ELISA, and Immunostaining to assess the therapeutic efficacy of stem cells for treating the aforementioned conditions.

Selected Publications:

1. Ghufran H, Azam M, Mehmood A, Ashfaq R, Baig MT, Malik K, Shahid AA, Riazuddin S. Tumoricidal effects of unprimed and curcumin-primed adipose-derived stem cells on human hepatoma HepG2 cells under oxidative conditions. Tissue and Cell. 2022 Oct 31:101968. Impact Factor: 2.586
2. Baig MT, Ghufran H, Mehmood A, Azam M, Humayun S, Riazuddin S. Vitamin E pretreated Wharton’s jellyderived mesenchymal stem cells attenuate CCl4-induced hepatocyte injury in vitro and liver fibrosis in vivo. Biochemical Pharmacology. 2021 Apr 1;186:114480. Impact Factor: 5.858
3. Riazuddin S, Baig MT, Mehmood A. 7. Cell therapy for liver regeneration. In Stem Cells–From Hype to Real Hope 2018 Dec 17 (pp. 130-145). De Gruyter.
4. Baig MT, Ali G, Awan SJ, Shehzad U, Mehmood A, Mohsin S, Khan SN, Riazuddin S. Serum from CCl4-induced acute rat injury model induces differentiation of ADSCs towards hepatic cells and reduces liver fibrosis. Growth Factors. 2017 Sep 3;35(4-5):144-60. Impact Factor: 2.511
5. Awan SJ, Baig MT, Yaqub F, Tayyeb A, Ali G. In vitro differentiated hepatic oval‐like cells enhance hepatic regeneration in CCl4‐induced hepatic injury. Cell biology international. 2016 Dec 13. Impact Factor: 3.612